Alteration in 5HT1A Receptor Activity from a Prenatal Exposure to Dexamethasone in a Stressed and Non-Stressed Adult Male Rat
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The Effect of Prenatal Exposure to Restraint Stress on Hippocampal Granule Neurons of Adult Rat Offspring
Objective(s) It is well known that prenatal stresses (PS) induce a variety of neurobiological and behavioral alterations, some of them involving the hippocampal formation. This study aimed to determine whether restraint stress influences the neuronal volume and number of granule cells in the hippocampus of adult rat offspring. Materials and Methods Ten Wistar pregnant rats were randomly divi...
متن کاملThe effect of prenatal restraint stress on the number and size of neurons in the rat hippocampal subdivisions
Animal studies have shown that prenatal stress is able to induce long-lasting neurobiological and behavioral alterations in adult offspring. In spite of the facts that hippocampus is sensitive to early developmental influences and its known functional importance in learning and memory, few data are available on the effect of prenatal stress on the structure of hippocampus. Therefore, this study...
متن کاملThe effect of prenatal restraint stress on the number and size of neurons in the rat hippocampal subdivisions
Animal studies have shown that prenatal stress is able to induce long-lasting neurobiological and behavioral alterations in adult offspring. In spite of the facts that hippocampus is sensitive to early developmental influences and its known functional importance in learning and memory, few data are available on the effect of prenatal stress on the structure of hippocampus. Therefore, this study...
متن کاملEffect of Restraint Stress during Gestation on Pentylenetetrazol-Induced Epileptic Behaviors in Rat Offspring
Objective(s): Epilepsy is a neurodevelopmental disorder which is strongly influenced by genetic and environmental factors. Gestational stress has been shown to be an important factor for affecting seizure susceptibility. The present study was conducted to address whether gestational stress may affect pentylentetrazol (PTZ)-induced epileptic behavior in rat offspring in a sex- and a...
متن کاملStereological analysis of cornu ammonis in prenatally stressed rats: a heuristic neurodevelopmental model of schizophrenia
Objective(s):The hippocampus has been implicated in pathophysiology of schizophrenia. Prenatal stress is a contributing risk factor for a wide variety of neuropsychiatric diseases including schizophrenia. This study examined long-term effects of prenatal restraint stress on the stereological parameters in the Cornu Ammonis (CA) of adult male rats as an animal model of schizophrenia. Materials ...
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تاریخ انتشار 2014